Iibka Kulul ee Cagaaran Budada Xannaanada Maqaarka CAS 302-79-4 Acid Retinoic Acid Qalab Ceyriin
Sharaxaada Alaabta
Retinoic Acid/Tretinoin waa qaabka aashitada ee fiitamiin A waxaana sidoo kale loo yaqaanaa all-trans retinoic acid ama ATRA. Waa daawo caadi ahaan loo isticmaalo daawaynta finanka vulgaris iyo keratosis pilaris. Waxa loo heli karaa kareem ahaan ama jel ahaan Waxa kale oo loo isticmaalaa in lagu daweeyo leukemia promyelocytic ba'an. Waxa kale oo loo heli karaa si guud.
Guusha ay ku leedahay daawaynta leukemia promyelocytic ba'an waxay ahayd horumar wayn oo laga gaaray daawaynta nooca leukemia-ga.Waxay ka shaqeysaa APL sababtoo ah inta badan kiisaska waxay ku lug leeyihiin tarjumaadda koromosoomyada ee koromosoomyada 15 iyo 17, taas oo sababta isku-dhafka hidda-wadaha ee hidda-wadaha retinoic acid. hidda-wadaha leukemia-ga promyelocytic.
Isku-dhafkan borotiinka PML-RAR wuxuu mas'uul ka yahay ka hortagga unugyada myeloid ee aan qaan-gaarin inay u kala soocaan unugyo badan oo qaan-gaar ah. Kala soocidaani waxaa loo maleynayaa inay keento leukemia.
COA
WAXYAABAHA | HEERKA | NATIIJADA IMTIXAANKA |
Qiimayn | 99% retinoic acid | waafaqsan |
Midabka | Budada Jaallaha ah | waafaqsan |
ur | Ma jiro ur gaar ah | waafaqsan |
Cabbirka walxaha | 100% dhaaf 80mesh | waafaqsan |
Luminta qalajinta | ≤5.0% | 2.35% |
Hadhaaga | ≤1.0% | waafaqsan |
Bir culus | ≤10.0pm | 7ppm |
As | ≤2.0pm | waafaqsan |
Pb | ≤2.0pm | waafaqsan |
Hadhaaga sunta cayayaanka | xun | xun |
Wadarta tirada saxanka | ≤100cfu/g | waafaqsan |
Khamiirka & Caaryada | ≤100cfu/g | waafaqsan |
E.Coli | xun | xun |
Salmonella | xun | xun |
Gabagabo | Waafaqi sifada | |
Kaydinta | Lagu kaydiyaa meel qabow & qallalan, ka fogow iftiinka xooggan iyo kulaylka | |
Nolosha shelf | 2 sano marka si fiican loo kaydiyo |
Shaqada
1. Retinoic Acid waa daawo caadi ahaan loo isticmaalo daawaynta finanka vulgaris iyo keratosis pilaris.
2. Retinoic Acid waxa loo heli karaa kareem ahaan ama jel ahaan. Waxa kale oo loo isticmaalaa in lagu daweeyo promyelocytic leukemia ba'an.
3. Retinoic Acid waxay kicin kartaa korriinka maqaarka waxayna ka dhigi kartaa mid caadi ah.
4. Retinoic Acid waxay hoos u dhigi kartaa habka gabowga maqaarka si loo caddeeyo, ka saara laalaabyada yaryar.
5. Retinoic Acid waxa ay yarayn kartaa qallafsanaanta maqaarka, markaa maqaarku waxa uu noqonayaa mid guduudan.
Codsiyada
1. Retinoic Acid/Tretinoin waxaa si weyn looga codsadaa goobta farmashiyaha, inta badan waxaa loo isticmaalaa daawaynta dermatonosus sida finanka, ichthyosis iyo psoriasis aan caadi ahayn, iwm.
2. Retinoic Acid /Tretinoin waxa laga samayn karaa tretinoin ama kareem retinoic acid si loo daweeyo maqaarka ama maqaarka kale ee aan caafimaad qabin.
3. Retinoic Acid/Tretinoin waxa loo isticmaalaa dawooyinka u adkaysta maqaarka keratinocytes iyo daawada kala duwanaanta unugyadu keento.
Alaabooyinka La Xiriira
Warshada Newgreen waxay sidoo kale bixisaa Amino acids sida soo socota: