Supply Newgreen Tayo Sare leh Algae-Brown Soosaar 98% Fucoidan Powder

Shaqada:

1. Waxay wanaajisaa xanuunka caloosha

Waxaa la ogaaday in saameynta polysaccharide ee cudurrada caloosha ay inta badan ka muuqatay saddexda dhinac ee soo socda: (1) Polysaccharide waxay saameyn ku yeelatay ka saarista Helicobacter pylori, ka hortagga faafidda Helicobacter pylori waxayna ka hortagtaa ku-xidhka xuubka caloosha; (2) Waxay leedahay saamaynta ilaalinta xabka gastric iyo daawaynta boogaha gastric, waxayna leedahay saameyn wanaagsan oo yaraynta khamriga iyo dhaawaca xabka caloosha ee daroogada iyo boogaha gastric ee raaga; (3).

2. Saamaynta xinjirowga lidka ku ah

Fucoidan waxa uu leeyahay hawlo badan oo bayooloji ah, laakiin hawsheeda xinjirowga lidka ku ah ayaa ah tan ugu ballaadhan ee la barto. Daraasaduhu waxay muujiyeen in polysaccharides-ka laga soo saaro algae brown Marine kala duwan ay leeyihiin heerar kala duwan oo ah hawlaha xinjirowga lidka ku ah. Tusaale ahaan, polysaccharides-ka oo ka soo jeeda oo muujiyay heer sare oo firfircoonida xinjirowga lidka ku ah, iyo waxqabadka xinjirowga lidka ku ah oo ahaa kala badh kii hore, laakiin ku dhawaad ​​ma laha waxqabad xinjirowga lidka ku ah.

3. Saamaynta Antithrombotic

Qaabka tijaabada ah ee xayawaanka nool, polysaccharide ee fucoidan waxay leedahay saameyn xannibaad ah oo ku saabsan xinjirowga xididada iyo xinjirowga dhiigga labadaba. Rocha iyo al. waxay ogaatay in polysaccharide uusan lahayn wax qabad xinjirowga lidka ku ah in vitro, laakiin wuxuu muujiyay saameyn cad oo antithrombotic ah oo ku saabsan qaabka xayawaanka ee samaynta xinjirowga xididada, saameyntuna waxay ku xiran tahay waqti, taasoo gaartay ugu badnaan ka dib 8h ee maamulka. Dhaqdhaqaaqa xinjirowga lidka ku ah ee polysaccharide waxay u badan tahay inay la xiriirto kicinta soo saarista heparin sulfate ee unugyada endothelial.

4. Saamaynta fayraska

Daraasaduhu waxay muujiyeen in polysaccharides sulfated (oo ay ku jiraan fucoidan polysaccharides) ay muujiyaan firfircoonida fayraska labadaba gudaha vivo iyo in vitro. Hayashi iyo al. wuxuu bartay saamaynta difaaca fucoidan ee fayraska herpes simplex (HSV). Waxay ogaadeen in fucoidan ay ka ilaalin karto jiirarka infekshanka HSV, waxayna tilmaameen in fucoidan laga yaabo inay ka hortagto caabuqa HSV iyadoo si toos ah u joojinaysa taranka fayraska iyo kor u qaadida shaqada difaaca jirka ee gudaha iyo helitaanka. Isla mar ahaantaana, waxaa sidoo kale la ogaaday in polysaccharide ay muujisay firfircoonida fayraska ee ka dhanka ah HSV-1 iyo HSV-2. Hidari iyo al. ayaa sheegay in fucoidan ay si wax ku ool ah u joojin karto caabuqa fayraska dengue nooca 2 (DEN2), waxayna muujisay in fucoidan ay ku xidhan tahay qaybaha DEN2 oo ay la falgasho baakadeeda glycoprotein. Ma laha saameyn toos ah oo ku saabsan virions, iyo habka ka hortagga fayraska waa in la joojiyo samaynta cytiocytes ee fayraska iyada oo la xakameynayo xayeysiiska fayraska.

5. Saamaynta ka hortagga burooyinka

Fucoidan waxaa loo arkaa inuu yahay wakiilka dabiiciga ah ee ka hortagga kansarka, iyo dhaqdhaqaaqeeda ka hortagga burooyinka ayaa la soo sheegay iyo in ka badan. Alekseyenko iyo al. wuxuu bartay dhaqdhaqaaqa ka hortagga buro ee fucoidan ee jiirarka la ildaran Lewis sambabada adenocarcinoma, oo fucoidan lagu quudiyo qiyaasta 10mg/kg ee jiirarka, taasoo keentay firfircoonida ka hortagga burooyinka dhexdhexaadka ah iyo saamaynta metastasis-ka-hortagga ee burooyinka. Daraasadaha qaar ayaa sidoo kale lagu ogaaday in heerka xannibaadda buro ee fucoidan ee 5 xayawaan ah oo ay ku jiraan S180 sarcoma ay ahayd 30%, iyo sarcoma 2 xayawaan ah ayaa gebi ahaanba hoos u dhacday. Saxan petri ah oo ku saabsan 10,000 unugyada kansarka mindhicirka oo lagu daaweeyay algae polysaccharides ee dabiiciga ah ee laga helay kelp, 50 boqolkiiba unugyada kansarka ayaa dhintay 24 saacadood ka dib, ku dhawaad ​​dhammaan unugyada kansarka ayaa dhintay 72 saacadood ka dib. Hyun iyo al. waxaa la ogaaday in polysaccharide ee algae dhagaxa ay si weyn u joojin karto koritaanka unugyada kansarka mindhicirka ee HCT-15. Ka dib markii lagu daaweeyo xariiqda unugyada HCT-15 oo leh algae polysaccharide, dhacdooyinka apoptotic sida jebinta DNA, isku-darka koromosoomyada, iyo kororka unugyada subdiploid ee wajiga G1 ayaa soo muuqday.

6. Saamaynta Antioxidant

Tijaabooyin badan oo vitro ah ayaa muujiyay in polysaccharide ee algae dhagaxa ay leedahay firfircoonida antioxidant ee muhiimka ah, waa nooc ka mid ah antioxidant-ka dabiiciga ah, waxayna si wax ku ool ah uga hortagi kartaa cudurka ay keenaan xagjirrada xorta ah. Costa iyo al. polysaccharides sulfated oo laga soo saaray 11 nooc oo ah geedo badeed kulaylaha ah, kuwaas oo dhamaantood lahaa firfircoonida antioxidant, awood u leh inay sameeyaan chelates ferrous iyo yaraynta awooda, 5 ka mid ah kuwaas oo awood u leh inay ka saaraan radicals hydroxyl, iyo 6 ka mid ah kuwaas oo awood u leh inay ka saaraan peroxy radicals. Micheline iyo al. ayaa sheegay in polysaccharides-ka algae-ga ay joojin karaan samaynta radical hydroxyl iyo radical superoxide.

7. Dhaqdhaqaaqa difaaca jirka

Fucoidan waxay leedahay hawlo badan oo difaac ah, oo ay ku jiraan waxqabadka ka-hortagga dhammaystirka, jawaab-celinta ka-hortagga bararka iyo saamaynta immunomodulatory. Tissot iyo al. ayaa la xaqiijiyay in polysaccharide ee fucoite ay joojin karto borotiinka dhammaystirka ah ee serum caadiga ah ee bini'aadamka, sidaas awgeed waxay joojinaysaa kala dirida unugyada dhiigga cas ee idaha oo ay sababtay firfircoonida dhamaystirka, iyo joojinta kicinta dhamaystirka iyada oo la joojinayo tallaabada ugu horreysa ee dariiqa dhaqdhaqaaqa qadiimiga ah (oo ay ku jiraan qaybta koowaad ee dhamaystirka, qaybta labaad iyo qaybta afraad). Yang iyo al. la ogaaday in fucoidan uu si xushmad leh u joojin karo muujinta nitric oxide synthase ee unugyada bararka oo uu leeyahay dhaqdhaqaaq ka hortag ah. Mizuno iyo al. loo isticmaalo nidaamka co-dhaqanka ee unugyada epithelial mindhicirka Caco-2 iyo macrophage RAW264.7 si ay u qiimeeyaan saamaynta anti-bararka ee arrimaha cuntada, iyo natiijooyinku waxay muujiyeen in polysaccharide ee S. japonicum kicin karaa wax soo saarka ee buro necrosis factor.α gudaha RAW264.7, taas oo ka hortagaysa muujinta mRNA ee interleukin ee unugyada Caco-2.

8. Hagaajinta tayada shahwada

Maamulka fucoidan wuxuu wanaajin karaa tayada shahwada iyo tirada iyadoo la hagaajinayo dheef-shiid kiimikaadka dhiigga iyo microbiota xiidmaha. Cilmi-baadhayaashu waxay ogaadeen in ka dib markii lagu maamulo polysaccharides badeed, heerarka muujinta hidde-sideyaasha ee la xidhiidha spermatogenesis ayaa si weyn u kordhay xiniinyaha jiirarka. Isla mar ahaantaana, waxaa jiray xiriir wanaagsan oo ka dhexeeya microbiota mindhicirka iyo dheef-shiid kiimikaadka dhiigga. Iyadoo la xakameynayo labadaba, polysaccharide ee fucoite waxay hagaajisay dheef-shiid kiimikaad ee xiniinyaha, kor u kaca ilaalinta antioxidant, iyo kor u qaadida heerka muujinta hiddo-wadaha la xidhiidha unugyada jeermiska, sidaas darteed gacan ka geysta spermatogenesis iyo hagaajinta tayada.